Dextron Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Deferasirox

Indications/Uses

Chronic Fe overload due to blood transfusions (transfusional hemosiderosis).

Dosage/Direction for Use

Initially 20 mg/kg once daily.

Administration

Should be taken on an empty stomach: Take at least 20 min before meals.

Contraindications

Hypersensitivity. CrCl <40 mL/min or >2 times the age-appropriate ULN.

Special Precautions

Ulcers w/ GI perforation. SJS, erythema multiforme, skin rashes. Risk of acute renal failure, renal tubulopathy. Hepatic failure.

Adverse Reactions

Increased blood creatinine. Headache; diarrhea, constipation, vomiting, nausea, abdominal pain or distention, dyspepsia, increased transaminases; rash; pruritus; proteinuria.

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Drug Interactions

Not to be used concomitantly w/ other Fe chelator therapies.

MIMS Class

Antidotes & Detoxifying Agents

ATC Classification

V03AC03 - deferasirox ; Belongs to the class of iron chelating agents. Used in the management of chronic iron overload associated with blood transfusion.

Regulatory Classification

Presentation/Packing

Form

Dextron tab 250 mg

Packing/Price

3 × 10's (Rp270,000/boks)

Form

Dextron tab 500 mg

Packing/Price

3 × 10's (Rp1,725,000/boks)

Dextron

deferasirox

Manufacturer:

Novell Pharma