Clozax Dosage & Drug Information

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Concise Prescribing Info

Contents

Clozapine

Indications/Uses

Resistant schizophrenia.

Dosage/Direction for Use

Initially 12.5 mg once or twice on the 1st day, followed by 1 or 2 25-mg tab on the 2nd day. Dose may be gradually increased by 25-50 mg until 300 mg daily w/in 2-3 wk, may be further increased by 50-100 mg at ½-wkly or wkly intervals.

Administration

May be taken with or without food.

Special Precautions

Hypersensitivity. Uncontrolled epilepsy. Myeloproliferative disorders. Bone marrow dysfunction.

Adverse Reactions

Nausea, vomiting, constipation.

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Drug Interactions

Concomitant use w/ MAOIs, alcohol, cimetidine, phenytoin.

MIMS Class

Antipsychotics

ATC Classification

N05AH02 - clozapine ; Belongs to the class of diazepines, oxazepines and thiazepines antipsychotics.

Regulatory Classification

Presentation/Packing

Form

Clozax caplet 100 mg

Packing/Price

3 × 10's

Form

Clozax caplet 25 mg

Packing/Price

3 × 10's

Clozax

clozapine

Manufacturer:

Simex