Clindamycin should be reserved for serious infections.
Clindamycin it should not be used in patients with upper respiratory tract infections.
Used with caution individuals with a history of gastrointestinal disease, particularly colitis.
Patients with hepatic or renal impairment dosage may be decreases because in this patients serum half-life of Clindamycin may be prolonged.
Prescribed with caution in elderly patients, they should be monitored for change in bowel frequency because in elderly patients with severe infections sensitive to diarrhea.
Prescribed with caution in atopic individuals.
The use of Clindamycin occasionally results in overgrowth of non-susceptible organism particularly yeasts. Should superinfections occur, appropriate measure should be taken as indicated by the clinical situation.
In surgical procedures should be performed in conjunction with antibiotic therapy.
During prolonged therapy, periodic liver and kidney function tests and blood counts should be monitored during high-dose therapy.
Since Clindamycin does not diffuse adequately into the cerebrospinal fluid, the drug should not be used in the treatment of meningitis.
Clindamycin is excreted into breast milk, because of the potential for adverse reactions in nursing neonatus from Clindamycin, a decision should be made whether to continue or discontinue nursing, taking into account the importance of the drug.
In patients with severe renal disease accompanied by severe metabolic disorders, medication doses should be given with caution, and serum Clindamycin levels should be monitored during high-dose treatment.
Giving the newborn to do proper observation of organ function. For injection containing Benzyl alcohol additives can cause Gasping Syndrome in premature infants.
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