Co-amoxiclav (amoxicillin & clavulanic acid). Per 500 mg FC caplet Amoxicillin 500 mg, clavulanic acid 125 mg. Per 5 mL dry syr Amoxicillin 125 mg, clavulanic acid 31.25 mg. Per 5 mL Forte dry syr Amoxicillin 250 mg, clavulanic acid 62.5 mg
CapletAdult & childn >12 yr Mild to moderate infections: 250 mg 3 times daily. Severe infections: 500 mg 3 times daily. Childn Usual recommended dose: 25 mg/kg/day 8 hrly in divided doses. Dental infectionsAdult & childn >12 yr 250 mg 3 times daily for 5 days. Renal impairment:Moderate (CrCl 10-30 mL/min) 250-500 mg 12 hrly. Severe (CrCl <10 mL/min) Max: 250 mg tab 12 hrly. Dry syr1-6 yr 5 mL. Childn <1 yr 2.5 mL. Forte dry syrChildn >6 yr 5 mL. Doses of syr should be taken 3 times daily.
Administration
May be taken with or without food: Best taken at the start of meals for better absorption & to reduce GI discomfort.
Contraindications
Hypersensitivity to penicillin; neonates whose mothers are hypersensitive to penicillins or its derivatives; history of cholestatic jaundice (hepatic dysfunction).
Special Precautions
Avoid prolonged use. Severe hepatic impairment, moderate or severe renal impairment. Pregnancy & lactation.
J01CR02 - amoxicillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.
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