Aricept Evess Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Donepezil HCl

Indications/Uses

Symptomatic treatment of mild, moderate & severe Alzheimer's disease (AD).

Dosage/Direction for Use

Adult & elderly Mild to moderate Alzheimer's disease Initially 5 mg/day in the evening (prior to retiring). Dose can be increased to 10 mg/day after at least 1 mth of clinical assessment of treatment at 5 mg/day. Max: 10 mg/day. Severe Alzheimer's disease 10 mg/day, only after daily dose of 5 mg for 4-6 wk. If not tolerated, reduce to 5 mg.

Administration

May be taken with or without food: Place on the tongue & allow to disintegrate before swallowing w/ or w/o water.

Contraindications

Hypersensitivity to piperidine derivatives.

Special Precautions

Underlying cardiac condition abnormalities, history of ulcer disease or those receiving concurrent NSAIDs, history of asthma or obstructive pulmonary disease. May impair ability to drive or operate machinery. Pregnancy & lactation.

Adverse Reactions

Diarrhea, muscle cramps, fatigue, nausea, vomiting, insomnia, headache, anorexia, hallucination, agitation, aggressive behavior, depression, abnormalities, somnolence, syncope, dizziness, abdominal disturbance, rash, pruritus, urinary incontinence, pain, decreased wt, ecchymosis, infection.

View ADR Reporting Link

Drug Interactions

Anesth, ketoconazole, quinidine, dexamethasone, phenobarb, rifampicin, phenytoin, carbamazepine, drugs w/ anticholinergic activity, succinylcholine, other neuromuscular blockers or cholinergic agonists eg, bethanechol.

MIMS Class

Neurodegenerative Disease Drugs

ATC Classification

N06DA02 - donepezil ; Belongs to the class of anticholinesterases. Used in the management of dementia.

Regulatory Classification

Presentation/Packing

Form

Aricept Evess orodispersible tab 10 mg

Packing/Price

2 × 14's

Aricept Evess

donepezil

Manufacturer:

Eisai