Apidra Overdosage

Hypoglycemia may occur as a result of an excess of insulin activity relative to food intake and energy expenditure. There are no specific data available concerning overdose with insulin glulisine. However, hypoglycemia may develop over sequential stages: Mild hypoglycemia episodes can be treated by oral administration of glucose or sugary products. It is therefore recommended that the diabetic patients constantly carries some sugar lumps, sweets, biscuits or sugary fruit juice.
Severe hypoglycemia episodes, where the patients has become unconscious, can be treated by glucagon (0.5 to 1 mg) given intramuscularly or subcutaneously by a person who has received appropriate instruction, or by glucose given intravenously by a medical professional. Glucose must also be given intravenously, if the patients does not respond to glucagons within 10 to 15 minutes. Upon regaining consciousness, administration of oral carbohydrate is recommended for the patient in order to prevent relapse.
After an injection of glucagons, the patient should be monitored in a hospital in order to find the reason for this severe hypoglycemia and prevent other similar episodes.