Provision of amino acids in patients w/ acute or chronic renal failure & during hypoproteinemia, malnutrition, pre- & post-op.
Dosage/Direction for Use
Adult Usual dose: Chronic renal failure 200 mL/day via peripheral vein w/ infusion rate of 100 mL over 60 min (25 drops/min) or 400 mL/day via central vein by TPN. Acute renal failure 600 mL/day via central vein by TPN. >300 kCal of non-protein cal/g of nitrogen should be administered for efficiency of amino acid utilization. Childn, elderly, seriously ill patient Individualized dosage via slow infusion.
Contraindications
Risk of hepatic coma, hyperammonemia, inherited abnormal amino acid metabolism, severe renal disorder or azotemia.
Special Precautions
Cerebrovascular dysfunction, hepatic disorder or GI bleeding, severe acidosis or electrolyte imbalance or abdominal acid-base balance. Pregnancy. Childn. Elderly.
Adverse Reactions
Hypersensitivity reactions, nausea, vomiting, chest discomfort, palpitations, increased BUN or creatinine & liver enzymes, acidosis, chills, fever, flushing, headache, vascular pain, lower extremities edema, hyperkalemia & dry mouth. Increased GOT, GPT, γ-GTP, ALP, LDH, LAP, total bilirubin or ammonia.
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