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Erosive oesophagitis
Adult: 20 mg once daily for 4-8 weeks. Maintenance: 10 or 20 mg once daily depending on patient response.
Oral
Gastro-oesophageal reflux disease
Adult: Usual dose: 20 mg once daily for 4-8 weeks. Maintenance: 10 or 20 mg daily depending on the response. In patients with symptomatic disease without oesophagitis: 10 or 20 mg once daily for 4 weeks. Once symptoms have resolved, 10 mg once daily as needed.
Child: 1-11 years <15 kg: 5 mg once daily, may increase up to 10 mg once daily if necessary, for up to 12 weeks. ≥15 kg: 10 mg once daily for up to 12 weeks. ≥12 years 20 mg once daily for up to 8 weeks.
Child: 1-11 years <15 kg: 5 mg once daily, may increase up to 10 mg once daily if necessary, for up to 12 weeks. ≥15 kg: 10 mg once daily for up to 12 weeks. ≥12 years 20 mg once daily for up to 8 weeks.
Oral
Peptic ulcer
Adult: 20 mg once daily for 4-8 weeks (duodenal ulcer) or for 6-12 weeks (gastric ulcer).
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Eradication of Helicobacter pylori associated with peptic ulcer disease
Adult: In combination with clarithromycin 500 mg bid and amoxicillin 1 g bid: 20 mg bid for 7 days.
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Zollinger-Ellison syndrome
Adult: 60 mg once daily, may titrate up to 100 mg daily as single dose or up to 120 mg daily in 2 divided doses if necessary.
