There is no known antidote for VITRAKVI. The treatment of overdose with VITRAKVI should consist of general supportive measures.
In clinical trials, the highest single dose of VITRAKVI was 900 mg, which is equivalent to 9-times a single recommended dose when taken twice daily. Among 12 healthy adult subjects who received a single dose of either 700 or 900 mg VITRAKVI, adverse events reported in ≥ 2 subjects consisted of nausea, vomiting, dizziness, and headache.