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Vincristine sulphate is contraindicated: in patients who are hypersensitive to vincristine sulphate or to one of the excipients; in patients with neuromuscular disorders (such as the demyelinating form of Charcot-Marie-Tooth syndrome); in patients with a severe liver function disorder; in patients with constipation and impending ileus, especially in children; in patients who are treated with radiotherapy in which the liver is involved.
Careful notice should also be given to those conditions listed in Precautions.
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