Nitrolingual Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Glyceryl trinitrate

Indications/Uses

Acute angina attacks. Angina prophylaxis. Acute heart attacks. Acute heart failure, w/ acute left heart failure. Catheter-induced coronary spasms during coronary angiography.

Click to view Nitrolingual detailed prescribing information

Dosage/Direction for Use

SL Start of angina attack or immediately before stress known to trigger attack 0.4-1.2 mg (1-3 puffs), depending on severity. Acute heart failure & acute heart attack 0.4-1.2 mg (1-3 puffs), depending on severity, w/ monitoring of blood circulation (systolic BP >100 mmHg). Repeat same dose if no response after 10 min. Preventive measure before coronary angiography 0.4-0.8 mg (1-2 puffs).

Click to view Nitrolingual detailed prescribing information

Overdosage

View Nitrolingual overdosage for action to be taken in the event of an overdose.

Contraindications

Hypersensitivity to glyceryl trinitrate, other nitrate compd, or peppermint oil. Acute circulatory failure. Marked hypotension (systolic BP <90 mmHg). Cardiogenic shock, unless appropriate measures are in place to ensure a sufficiently high left-ventricular end diastolic pressure. Hypertrophic obstructive cardiomyopathy. Disorders associated w/ increased ICP (eg, head injuries, brain bleed). Severe anaemia. Concomitant use w/ phosphodiesterase-5 inhibitors.

Click to view Nitrolingual detailed prescribing information

Special Precautions

Do not inhale. Caution before using in patients w/ constrictive pericarditis or pericardial tamponade; low filling pressure eg, in acute heart attack, left-sided heart failure; aortic &/or severe mitral valve stenosis; risk of orthostatic hypotension; disorder affecting cerebral blood flow; early stages of glaucoma; left ventricular hypertrophy combined w/ aortic valve stenosis. Contains small amounts of ethanol (<10 mg/dose). May impair ability to drive or operate machinery. Pregnancy & lactation. No data in childn.

Click to view Nitrolingual detailed prescribing information

Use In Pregnancy & Lactation

Click to view Nitrolingual detailed prescribing information

Adverse Reactions

Nitrate-induced headache; decreased BP &/or orthostatic hypotension.

Drug Interactions

Increased antihypertensive effect w/ other vasodilators; antihypertensives (eg, β-blockers, Ca antagonists, diuretics, ACE inhibitors); TCAs or neuroleptics; alcohol; sapropterin; phosphodiesterase-5 inhibitors (eg, sildenafil, vardenafil). Enhanced vasodilatory effect w/ N-acetylcysteine. Patients previously treated w/ organic nitrates (eg, isosorbide dinitrate, isosorbide-5-mononitrate) may require higher dose of glyceryl trinitrate to achieve desired effect. Raised levels of dihydroergotamine. Weakened effect of heparin.

Click to view Nitrolingual detailed prescribing information

Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Nitrolingual detailed prescribing information

Storage

View Nitrolingual storage conditions for details to ensure optimal shelf-life.

Description

View Nitrolingual description for details of the chemical structure and excipients (inactive components).

Action

View Nitrolingual mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Anti-Anginal Drugs

ATC Classification

C01DA02 - glyceryl trinitrate ; Belongs to the class of organic nitrate vasodilators. Used in the treatment of cardiac disease.

Regulatory Classification

P₁

Presentation/Packing

Form

Nitrolingual spray 0.4 mg/dose

Packing/Price

(14.4 mL bottle) 200 dose x 1's

Nitrolingual

glyceryl trinitrate

Manufacturer:

G Pohl-Boskamp

Distributor:

HK Medical Supplies

Health Express