Mild to moderate inflammatory acne
Adult: As 4% gel: Apply to the affected area bid. Reduce application frequency to once daily or every other day if excessive skin dryness, irritation or peeling occurs.
Indications and Dosage
Topical/Cutaneous
Mild to moderate inflammatory acne Adult: As 4% gel: Apply to the affected area bid. Reduce application frequency to once daily or every other day if excessive skin dryness, irritation or peeling occurs.
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What are the brands available for Nicotinamide in Hong Kong?
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Special Precautions
Avoid contact with eyes and mucous membranes, including the nose and mouth. Pregnancy and lactation.
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Adverse Reactions
Skin and subcutaneous tissue disorders: Dry skin, pruritus, erythema, burning sensation, irritation.
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Action
Description:
Mechanism of Action: Nicotinamide is the chemical form of vitamin B3 and the physiologically active form of niacin. It has significant anti-inflammatory activity that demonstrated beneficial effects on inflammatory acne. Synonym(s): Niacinamide. |
Chemical Structure
![]() Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 936, Niacinamide. https://pubchem.ncbi.nlm.nih.gov/compound/Niacinamide. Accessed Feb. 25, 2025. |
Storage
Store below 25°C.
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MIMS Class
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References
Brayfield A, Cadart C (eds). Nicotinic Acid. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 11/12/2024. Freederm Treatment 4% w/w Gel (Diomed Developments Limited). MHRA. https://products.mhra.gov.uk. Accessed 11/12/2024. Joint Formulary Committee. Nicotinamide. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 11/12/2024.
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