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Nicotinamide


Generic Medicine Info
Indications and Dosage
Topical/Cutaneous
Mild to moderate inflammatory acne
Adult: As 4% gel: Apply to the affected area bid. Reduce application frequency to once daily or every other day if excessive skin dryness, irritation or peeling occurs.
What are the brands available for Nicotinamide in Hong Kong?
  • Papulex
Special Precautions
Avoid contact with eyes and mucous membranes, including the nose and mouth. Pregnancy and lactation.
Adverse Reactions
Skin and subcutaneous tissue disorders: Dry skin, pruritus, erythema, burning sensation, irritation.
Action
Description:
Mechanism of Action: Nicotinamide is the chemical form of vitamin B3 and the physiologically active form of niacin. It has significant anti-inflammatory activity that demonstrated beneficial effects on inflammatory acne.
Synonym(s): Niacinamide.
Chemical Structure

Chemical Structure Image
Nicotinamide

Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 936, Niacinamide. https://pubchem.ncbi.nlm.nih.gov/compound/Niacinamide. Accessed Feb. 25, 2025.

Storage
Store below 25°C.
MIMS Class
Acne Treatment Preparations
References
Brayfield A, Cadart C (eds). Nicotinic Acid. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 11/12/2024.

Freederm Treatment 4% w/w Gel (Diomed Developments Limited). MHRA. https://products.mhra.gov.uk. Accessed 11/12/2024.

Joint Formulary Committee. Nicotinamide. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 11/12/2024.

Disclaimer: This information is independently developed by MIMS based on Nicotinamide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2025 MIMS. All rights reserved. Powered by MIMS.com
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