Mirvaso Dosage/Direction for Use

Posology: One application per 24 hours, at any time suitable for the patient, for as long as facial erythema is present.
The maximum daily recommended dose is 1 g of gel in total weight, divided into five pea size amounts.
Special populations: Elderly patients: The experience of use of Mirvaso in patients aged above 65 years is limited (see also Adverse Reactions).
Paediatric population: The safety and efficacy of Mirvaso in children and adolescents aged less than 18 years have not been established. No data are available.
Mirvaso is contraindicated in children aged less than 2 years because of serious systemic safety risk (see Contraindications). Safety concerns related to the systemic absorption of brimonidine have also been identified for the age group 2 to 12 years (see Overdosage). Mirvaso should not be used in children or adolescents aged 2 to 18 years.
Method of administration: Cutaneous use only.
Cutaneous application of a small pea size amount of medicinal product to each of the five areas of the face: forehead, chin, nose, each cheek.
Mirvaso should be applied smoothly and evenly as a thin layer across the entire face avoiding the eyes, eyelids, lips, mouth and membrane of the inner nose. Mirvaso should be applied only to the face.
Hands should be washed immediately after applying the medicinal product.
Mirvaso can be used in conjunction with other cutaneous medicinal products for the treatment of inflammatory lesions of rosacea and with cosmetics. These products should not be applied immediately before the daily application of Mirvaso; they may be used only after the applied Mirvaso has dried.