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Known or suspected pregnancy.
Confirmed or suspected hormone dependent tumours including breast cancer.
Current or recurrent pelvic inflammatory disease.
Cervicitis.
Current genital infection.
Postpartum endometritis, infected abortion during the past three months.
Conditions associated with increased susceptibility to infections.
Cervical dysplasia.
Uterine or cervical malignancy.
Undiagnosed abnormal genital bleeding.
Congenital or acquired abnormality of the uterus including fibroids if they distort the uterine cavity.
Liver tumour or other acute or severe liver disease.
Acute malignancies affecting the blood or leukaemias except when in remission.
Recent trophoblastic disease while hCG levels remain elevated.
Hypersensitivity to the active substance or to any of the excipients.
Active or previous severe arterial disease, such as stroke or myocardial infarction is a contraindication when Mirena is used in conjunction with an oestrogen for HRT use.
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