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Irbegen Plus is a combination of two active substances, irbesartan and hydrochlorothiazide.
Irbesartan belongs to a group of medicines known as angiotensin II receptor antagonists. Angiotensin-II is a substance produced in the body that binds to receptors in blood vessels causing them to tighten. This results in an increase in blood pressure. Irbesartan prevents the binding of angiotensin-II to these receptors, causing the blood vessels to relax and the blood pressure to lower.
Hydrochlorothiazide is a thiazide diuretic that causes increased urine output and so causes a lowering of blood pressure.
The two active ingredients in Irbegen Plus work together to lower blood pressure further than if either was given alone.
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