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Pregnancy: Treatment with GLYPRESSIN during pregnancy is contraindicated (see Contraindications and Pharmacology: Toxicology: Preclinical Safety Data under Actions). GLYPRESSIN has been shown to cause uterine contractions and increased intrauterine pressure in early pregnancy and may decrease the uterine blood flow. GLYPRESSIN may have harmful effects on pregnancy and foetus.
Spontaneous abortion and malformation of the foetus have been shown in rabbits after treatment with GLYPRESSIN.
Breast-feeding: It is not known whether GLYPRESSIN is excreted in human breast milk. The excretion of GLYPRESSIN in milk has not been studied in animals. A risk to the suckling child cannot be excluded. A decision on whether to continue/discontinue breast-feeding or to continue/discontinue therapy with GLYPRESSIN should be made taking into account the benefit of breast-feeding to the child and the benefit of GLYPRESSIN therapy to the woman.
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