G-NiiB M3XTRA

G-NiiB M3XTRA formula (SMT04) is a patented formula against colorectal cancer (CRC)-inducing bacteria.
Developed by the Centre for Gut Microbiota Research of The Chinese University of Hong Kong.
Safety and effectiveness in human are proved by clinical test.
Empowered by 3 patents: Fight against the CRC-inducing bacteria (M3); Restore the gut physiological barrier, boost up the protection of gut; Microencapsulated to ensure live probiotics can be delivered and colonized in the gut.
Food supplement; gluten-free; no artificial flavours and colourings; non-GMO.
The product contains traces of milk.
Nutritional information: See table.

Click on icon to see table/diagram/image

M3 CRC-Associated Bacteria: M3 CRC-associated bacteria involve a group of pathogenic bacteria and good bacteria which has shown correlation with colorectal adenoma and colorectal cancer. This group of bacteria has been developed into the M3CRC colorectal cancer prediction test with remarkably high sensitivity.
The role of gut dysbiosis in colorectal carcinogenesis has been increasingly recognised: The gut microbiome of CRC patients is different from that of healthy people.
The transfer of gut microbiota from CRC patients to germ-free mice promotes tumorigenesis in the latter.
Problematic gut microbiota potentially triggers inflammatory cascades and oncogenic signalling.
Gut Dysbiosis & Colorectal Cancer: Enrichment of certain bacterial species in the gut has been identified to contribute to colorectal carcinogenesis by promoting inflammation, causing DNA damage, inducing tumor proliferation and protecting tumor from immune attack.
Probiotics, such as Bifidobacteria and Streptococci are found to be depleted in CRC patients. These bacteria are suggested to exert a protective effect against CRC.
Potential Mechanisms of Probiotics: Action in the Prevention and Treatment of CRC: Colonization resistance: Probiotics inhibit colonization of pathogenic bacteria by releasing antimicrobial peptides, lowering luminal pH and/or directly interacting with pathogens.
Immunomodulation: Probiotics can have distinct immunomodulatory effect to reduce colonic inflammation or enhance antitumor immunity.
Enhancement of gut barrier function: Probiotics increase mucin production and tight junction protein expression and promote epithelial restitution.
Benefits demonstrated in patients: After taking M3XTRA formula (SMT04) for 4 weeks: The level of CRC/adenoma-related bacteria decreased by 37.5%; the level of good bacteria increased by 42.6%; intestinal permeability decreased by 33.3%; restoring physiological barrier and preventing leaky gut.

A microbiome-precision M3 gut-protective probiotics and prebiotics formula. Guards the gut against M3 bad bacteria. Relieves gut problems including constipation, diarrhoea, and gastrointestinal discomfort. Restores the balance of gut microbiome. Suitable for pregnant and breastfeeding women.

One sachet daily or as directed by healthcare professionals. Sprinkle in water, non-fizzy and non-alcoholic drinks, or food (below 45°C). Consume with a meal. Suitable for patients recovering from chronic diseases.

People with lactose intolerance or aged below 2 are recommended to consult a physician before use.
Take the product at least 3 hours before or after taking antibiotics or as advised by a physician.

Store in a cool, dry place and avoid sunlight.

Supplements & Adjuvant Therapy

V06DX - Other combinations of nutrients ; Used as general nutrients.