Hypersensitivity to the active substance(s) or to any of the excipients listed in Description.
Systemic infections unless specific anti-infective therapy is employed.
Because of its marked effect on sodium retention, the use of Florinef in the treatment of conditions other than those indicated, is not advised.
Since Fludrocortisone acetate is a potent mineralocorticoid both the dosage and salt intake should be carefully monitored to avoid the development of hypertension, oedema or weight gain. Periodic checking of serum electrolyte levels is advisable during prolonged therapy.