However, it is important to take into account that Exforge HCT may increase the hypotensive effect of other antihypertensive agents.
See Tables 2a and 2b.
Click on icon to see table/diagram/image
Click on icon to see table/diagram/imageDual blockade of the RAAS with ARBs, ACE inhibitors or aliskiren: Clinical trial data have shown that dual blockade of the RAAS through the combined use of ACE inhibitors, ARBs or aliskiren is associated with a higher frequency of adverse events such as hypotension, hyperkalaemia and decreased renal function (including acute renal failure) compared to the use of a single RAAS-acting agent (see Contraindications, Precautions and Pharmacology: Pharmacodynamics under Actions).
Sign Out