Oral Phosphate and Active Vitamin D Analogs: Concomitant use of CRYSVITA with oral phosphate and/or active vitamin D analogs will increase phosphate concentrations greater than expected with CRYSVITA alone. This increase may result in hyperphosphatemia which can induce nephrocalcinosis.
Concomitant use of CRYSVITA with oral phosphate and/or active vitamin D analogs is contraindicated.