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Adults: The initial dose is in the range of 15-40 mg daily in divided doses, at 8-hourly intervals according to the severity of the disorder.
Improvement is usually seen in 1 to 3 weeks and control of symptoms is achieved in 1 to 3 months.
The dose is then gradually reduced to the smallest amount that will control the disease.
Usual maintenance doses are 5 to 15 mg daily.
Children: The usual initial dose for children is 0.75 mg per kg body-weight daily in three divided doses.
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