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Benzyl benzoate


Generic Medicine Info
Indications and Dosage
Topical/Cutaneous
Scabies
Adult: As 25% emulsion: Apply to the entire skin surface (excluding the face and neck), allow to dry, and re-apply after 24 hours without bathing. Wash off after 24 hours. A 2nd application within 5 days may be necessary. Alternatively, 3 applications 12 hourly may be made, followed by bathing 12 hours after the last application. As 25% lotion: Apply a sufficient amount with a brush to cover the whole body (excluding the face and head). Allow to dry, then wash off after 24 hours with warm water and soap. May repeat treatment after 5 days, if necessary. Dosage recommendations and available products may vary between countries (refer to specific product guidelines).
Child: As 25% lotion: 2-12 years Dilute with equal parts of water before application. Apply a sufficient amount with a brush to cover the whole body (excluding the face and head). Allow to dry, then wash off after 24 hours with warm water and soap. May repeat treatment after 5 days, if necessary; >12 years Same as adult dose. Dosage recommendations and available products may vary between countries (refer to specific product guidelines).

Topical/Cutaneous
Head lice
Adult: As 25% lotion: Apply a sufficient amount to thoroughly wet the hair and scalp. Wash off after 24 hours with shampoo and warm water. Use a fine-toothed comb to remove remaining nits from the hair. May repeat treatment after 7 days, if necessary. Dosage recommendations and available products may vary between countries (refer to specific product guidelines).
Child: As 25% lotion: 2-12 years Dilute with equal parts of water before application. Apply a sufficient amount to thoroughly wet the hair and scalp. Wash off after 24 hours with shampoo and warm water. Use a fine-toothed comb to remove remaining nits from the hair. May repeat treatment after 7 days, if necessary; >12 years Same as adult dose. Dosage recommendations and available products may vary between countries (refer to specific product guidelines).
Contraindications
Hypersensitivity.
Special Precautions
Patient with history of allergic reactions to other topical products. Children. Pregnancy and lactation.
Adverse Reactions
Significant: Hypersensitivity reaction.
Eye disorders: Eye irritation.
General disorders and administration site conditions: Application site irritation.
Skin and subcutaneous tissue disorders: Skin and mucous membrane irritation, contact dermatitis, erythematous rash.
Patient Counseling Information
Avoid contact with face, eyes, lips, and mucous membranes. Do not use on broken, irritated, inflamed, or secondarily infected skin.
Action
Description:
Mechanism of Action: Benzyl benzoate is an acaricide agent. Its exact mechanism of action is unclear; however, it is known to be toxic to the CNS of parasites. Additionally, benzyl benzoate has an ovicidal activity.
Chemical Structure

Chemical Structure Image
Benzyl benzoate

Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 2345, Benzyl Benzoate. https://pubchem.ncbi.nlm.nih.gov/compound/Benzyl-Benzoate. Accessed June 26, 2025.

Storage
Store below 30°C. Protect from light.
MIMS Class
Topical Antifungals & Antiparasites
ATC Classification
P03AX01 - benzyl benzoate ; Belongs to the class of other ectoparasiticides including scabicides.
References
Benzyl Benzoate. UpToDate Lexidrug, Lexi-Drugs Multinational Online. Waltham, MA. UpToDate, Inc. https://online.lexi.com. Accessed 02/06/2025.

Brayfield A, Cadart C (eds). Benzyl Benzoate. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 02/06/2025.

Joint Formulary Committee. Benzyl Benzoate. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 02/06/2025.

Ridped Lotion (Winwa Medical Sdn. Bhd.). National Pharmaceutical Regulatory Agency - Ministry of Health Malaysia. https://www.npra.gov.my. Accessed 02/06/2025.

Scabitone Emulsion (SM Pharmaceuticals Sdn. Bhd.). National Pharmaceutical Regulatory Agency - Ministry of Health Malaysia. https://www.npra.gov.my. Accessed 02/06/2025.

Disclaimer: This information is independently developed by MIMS based on Benzyl benzoate from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2025 MIMS. All rights reserved. Powered by MIMS.com
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