Tizan Dosage & Drug Information

Indications/Uses

Painful muscle spasm associated w/ static & functional disorders of the spine (cervical & lumbar syndromes), following surgery eg, herniated intervertebral disc or OA of the hip, & spasticity due to neurological disorders eg, multiple sclerosis. Chronic myelopathy, CVA, cerebral palsy.

Dosage/Direction for Use

Painful muscle spasm 2 mg tid. Spasticity due to neurological disorder Initially 6 mg in 3 divided doses. Increase stepwise by 2-4 mg at ½-wkly or wkly intervals. (For optimum therapeutic response, 12-24 mg in 3-4 equally spaced doses). Max: 36 mg/day. Renal/hepatic insufficiency Initially 2 mg once daily.

Administration

May be taken with or without food.

Special Precautions

Renal insufficiency or severely impaired renal function. May affect ability to drive or operate machinery.

Adverse Reactions

Drowsiness, fatigue, dizziness, dry mouth, nausea, GI disturbances, slight reduction in BP. Muscle weakness & insomnia, hypotension & bradycardia.

View ADR Reporting Link

Drug Interactions

May cause hypotension & bradycardia when taken w/ antihypertensives including diuretics. May enhance sedative action w/ alcohol or other sedatives.

MIMS Class

Muscle Relaxants

ATC Classification

M03BX02 - tizanidine ; Belongs to the class of other centrally-acting muscle relaxants.

Thai FDA Category

D

Presentation/Packing

Form

Tizan tab 2 mg

Packing/Price

5 × 10's

Form

Tizan tab 4 mg

Packing/Price

5 × 10's

Tizan

tizanidine

Manufacturer:

Sun Pharma

Distributor:

DKLL

Marketer:

Ranbaxy