Zinnat Dosage & Drug Information

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Core Prescribing Info

Contents

Cefuroxime axetil

Indications/Uses

URTI (ENT infections eg, otitis media, sinusitis, tonsillitis & pharyngitis). Lower resp tract infections (eg, pneumonia & acute exacerbations of COPD). GUT (eg, pyelonephritis, cystitis & urethritis). Gonorrhoea, acute uncomplicated gonococcal urethritis & cervicitis. Skin & soft tissue infections (eg, furunculosis, pyoderma & impetigo).

Dosage/Direction for Use

Usual course of therapy: 7 days (5-10 days). Adult & childn ≥40 kg Acute tonsillitis & pharyngitis 250 mg bd. Community-acquired pneumonia, acute otitis media, bacterial sinusitis or exacerbations of COPD 500 mg bd. UTI, skin & soft tissue infections 250-500 mg bd. Uncomplicated gonorrhoea 1 g as single dose. Childn FC tab 20-40 kg Acute tonsillitis & pharyngitis 250 mg bd. Acute otitis media or bacterial sinusitis, community-acquired pneumonia, UTI, skin & soft tissue infection 250-500 mg bd. Oral susp Acute tonsillitis & pharyngitis 10 mg/kg bd. Max: 500 mg daily. Acute otitis media or bacterial sinusitis, community-acquired pneumonia, UTI, skin & soft tissue infections 15 mg/kg bd. Max: 1,000 mg daily. Renal impairment: CrCl 10-29 mL/min Standard individual dose every 24 hr, <10 mL/min Standard individual dose every 48 hr, during haemodialysis Single additional standard individual dose at the end of each dialysis.

Administration

Should be taken with food: FC tab: Swallow whole, do not crush/split.

Contraindications

Hypersensitivity to cephalosporins.

MIMS Class

Cephalosporins

ATC Classification

J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.

Regulatory Classification

POM

Presentation/Packing

Form

Zinnat FC tab 250 mg

Packing/Price

1's

Form

Zinnat FC tab 500 mg

Packing/Price

1's

Form

Zinnat granules for oral susp 125 mg/5 mL

Packing/Price

1's

Zinnat

cefuroxime

Manufacturer:

Glaxo Wellcome Operations