Xerava Dosage & Drug Information

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Core Prescribing Info

Contents

Eravacycline

Indications/Uses

Complicated intra-abdominal infections (cIAI) caused by susceptible microorganisms: E. coli, Klebsiella pneumoniae, Citrobacter freundii, Enterobacter cloacae, Klebsiella oxytoca, Enterococcus faecalis, Enterococcus faecium, Staph aureus, Strep anginosus group, Clostridium perfringens, Bacteroides spp & Parabacteroides distasonis in patients ≥18 yr.

Dosage/Direction for Use

IV Adult 1 mg/kg every 12 hr as an infusion over approx 60 min. cIAI Recommended duration of treatment: 4-14 days. Concomitant use of strong CYP3A inducer 1.5 mg/kg every 12 hr for 4-14 days. Severe hepatic impairment (Child-Pugh C) 1 mg/kg every 12 hr on day 1 followed by 1 mg/kg every 24 hr starting on day 2 for a total duration of 4-14 days.

Contraindications

Hypersensitivity to eravacycline & tetracyclines.

MIMS Class

Tetracyclines

ATC Classification

J01AA13 - eravacycline ; Belongs to the class of tetracyclines. Used in the systemic treatment of infections.

Regulatory Classification

POM

Presentation/Packing

Form

Xerava powd for conc for soln for infusion 50 mg

Packing/Price

1's

Xerava

eravacycline

Manufacturer:

Patheon Manufacturing Services LLC