Winrevair Dosage & Drug Information

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Core Prescribing Info

Contents

Sotatercept

Indications/Uses

Adults w/ pulmonary arterial HTN [World Health Organization (WHO) Group 1; Functional Class II to III] to increase exercise capacity, improve WHO functional class & delay disease progression.

Dosage/Direction for Use

SC Starting dose: 0.3 mg/kg every 3 wk. Patient weighing 174.2-180 kg 1.1 mL, 157.5-174.1 kg 1 mL, 140.9-157.4 kg 0.9 mL, 124.2-140.8 kg 0.8 mL, 107.5-124.1 kg 0.7 mL, 90.9-107.4 kg 0.6 mL, 74.2-90.8 kg 0.5 mL, 57.5-74.1 kg 0.4 mL, 40.9-57.4 kg 0.3 mL, 30-40.8 kg 0.2 mL. Target dose: 0.7 mg/kg every 3 wk. Patient weighing ≥167.5 kg 2.4 mL, 160.4-167.4 kg 2.3 mL, 153.3-160.3 kg 2.2 mL, 146.1-153.2 kg 2.1 mL, 139-146 kg 2 mL, 131.8-138.9 kg 1.9 mL, 124.7-131.7 kg 1.8 mL, 117.5-124.6 kg 1.7 mL, 110.4-117.4 kg 1.6 mL, 103.3-110.3 kg 1.5 mL, 96.1-103.2 1.4 mL, 89-96 kg 1.3 mL, 81.8-88.9 kg 1.2 mL, 74.7-81.7 kg 1.1 mL, 67.5-74.6 kg 1 mL, 60.4-67.4 kg 0.9 mL, 53.3-60.3 kg 0.8 mL, 46.1-53.2 kg 0.7 mL, 39-46 kg 0.6 mL, 31.8-38.9 kg 0.5 mL, 30-31.7 kg 0.4 mL.

MIMS Class

Other Antihypertensives

ATC Classification

C02KX06 - sotatercept ; Belongs to the class of other antihypertensives. Used in the treatment of pulmonary arterial hypertension.

Regulatory Classification

POM

Presentation/Packing

Form

Winrevair powd for soln for inj (powder vial) 45 mg

Packing/Price

1's

Form

Winrevair powd for soln for inj (powder vial) 60 mg

Packing/Price

1's

Form

Winrevair powd for soln for inj 45 mg

Packing/Price

1's

Form

Winrevair powd for soln for inj 60 mg

Packing/Price

1's

Winrevair

Manufacturer:

Patheon Italia