Ticaspan Dosage & Drug Information

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Core Prescribing Info

Contents

Ticagrelor

Indications/Uses

In combination w/ ASA for prevention of thrombotic events (CV death, MI & stroke) in patients w/ acute coronary syndromes (ACS) (unstable angina, non-ST elevation MI or ST elevation MI); including patients managed medically & those who are managed w/ percutaneous coronary intervention or CABG.

Dosage/Direction for Use

ACS Loading dose: 180 mg & then continued at 90 mg bd. Recommended for at least 12 mth unless discontinuation is clinically indicated. Patients w/ MI initiated on 90 mg Continue treatment w/ 60 mg w/o interruption if they have a high risk of an atherothrombotic event after 1 yr. Take a daily low maintenance dose of ASA 75-150 mg unless specifically contraindicated.

Administration

May be taken with or without food: Swallow whole. May crush to a fine powd & mix in half a glass of water. Administer mixt orally or via nasogastric tube. Take immediately.

Contraindications

Hypersensitivity. Active pathological bleeding. History of intracranial haemorrhage. Co-administration w/ strong CYP3A4 inhibitors (eg, ketoconazole, clarithromycin, nefazodone, ritonavir, atazanavir). Severe hepatic impairment.

MIMS Class

Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics)

ATC Classification

B01AC24 - ticagrelor ; Belongs to the class of platelet aggregation inhibitors excluding heparin. Used in the treatment of thrombosis.

Regulatory Classification

POM

Presentation/Packing

Form

Ticaspan FC tab 90 mg

Packing/Price

1's

Ticaspan

Manufacturer:

USV