Postmenopausal women w/ osteoporosis who are at high risk for fracture or who have failed or are intolerant of previous osteoporosis therapy. Increases bone mineral density & reduces risk of vertebral & nonvertebral fractures in postmenopausal women w/ osteoporosis. Increases bone mass in men w/ primary or hypogonadal osteoporosis who are at high risk for fracture including those w/ history of osteoporotic fracture, who have multiple risk factors for fracture or who have failed or are intolerant to previous osteoporosis therapy. Men & women w/ glucocorticoid-induced osteoporosis at high risk for fracture.