Hypersensitivity. Not to be given in patients who have had MI or ischaemic heart disease (IHD), Prinzmetal's angina/coronary vasospasm, peripheral vascular disease or those who have symptoms or signs consistent w/ IHD. Not to be administered to patients w/ previous CVA or transient ischaemic attack. Patients w/ uncontrolled HTN. Concomitant use w/ ergotamine or its derivatives (including methysergide). Concurrent administration w/ MAOIs; not to be used w/in 2 wk of therapy discontinuation w/ MAOIs. Severe hepatic impairment.