Seltavir

Patients ≥1 yr who present w/ symptoms typical of flu. Post-exposure prevention in individuals ≥1 yr following contact w/ clinically diagnosed flu case.

Flu treatment Adult & adolescent 13-17 yr 75 mg bd for 5 days. Adult & adolescent 13-17 yr w/ moderate to severe renal impairment: CrCl >60 mL/min 75 mg bd, >30 to ≤60 mL/min 30 mg bd, >10 to ≤30 mL/min 30 mg once daily. Hemodialysis patient 30 mg after each hemodialysis session. Peritoneal dialysis patient 30 mg single dose. Infant >1 yr & childn 2-12 yr weighing >40 kg 75 mg bd for 5 days, >23-40 kg 60 mg bd for 5 days, >15-23 kg 45 mg bd for 5 days, ≤15 kg 30 mg bd for 5 days. Childn 6-12 mth 3 mg/kg bd for 5 days. Flu prevention Adult & adolescent 13-17 yr 75 mg bd for 10 days. Adult & adolescent 13-17 yr w/ moderate to severe renal impairment: CrCl >60 mL/min 75 mg once daily, >30 to ≤60 mL/min 30 mg once daily, >10 to ≤30 mL/min 30 mg every 2nd day. Hemodialysis patient 30 mg after each 2nd hemodialysis session. Peritoneal dialysis patient 30 mg once wkly. Infant >1 yr & childn 2-12 yr weighing >40 kg 75 mg once daily for 10 days, >23-40 kg 60 mg once daily for 10 days, >15-23 kg 45 mg once daily for 10 days, ≤15 kg 30 mg once daily for 10 days. Prevention during flu epidemic in the community 75 mg once daily for up to 6 wk. Infant 6-12 yr Individualized dosage. Prepare compounded susp (10 mg/mL) based upon patient's wt, weighing ≥10 kg 3 mL bd for 5 days, 9 kg 2.7 mL bd for 5 days, 8 kg 2.4 mL bd for 5 days, 7 kg 2.1 mL bd for 5 days, 6 kg 1.5 mL bd for 5 days.

May be taken with or without food: For patient who are unable to swallow, may open cap & pour contents into a suitable, small amount (1 tsp max) of sweetened food product to mask bitter taste. Stir mixture & take immediately.

Hypersensitivity.

Antivirals

J05AH02 - oseltamivir ; Belongs to the class of neuraminidase inhibitors. Used in the systemic treatment of viral infections.

POM