Premarin Tablet Dosage & Drug Information

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Core Prescribing Info

Contents

Conjugated estrogens

Indications/Uses

Moderate to severe vasomotor symptoms associated w/ estrogen deficiency. Prevention & management of osteoporosis associated w/ estrogen deficiency. Atrophic vaginitis & urethritis. Female hypoestrogenism.

Dosage/Direction for Use

Administer the lowest effective dose. Vasomotor symptoms; atrophic vaginitis & urethritis associated w/ estrogen deficiency 0.3-1.25 mg daily. Osteoporosis 0.3-0.625 mg daily. Female hypoestrogenism 0.3-1.25 mg daily, administer cyclically (eg, 3 wk on & 1 wk off) & adjust depending on severity of symptoms & endometrial responsiveness.

Administration

May be taken with or without food: Swallow whole, do not divide/crush/chew/dissolve.

Contraindications

Hypersensitivity. Known, suspected or history of breast cancer. Known or suspected estrogen-dependent neoplasia (eg, endometrial cancer or hyperplasia). Undiagnosed abnormal uterine bleeding. Active or history of arterial thromboembolic disease (eg, stroke, MI) or VTE (eg, DVT, pulmonary embolism). Known thrombophilic disorders (eg, protein C or S, or antithrombin deficiency). Active or chronic liver dysfunction or disease. Known or suspected pregnancy.

MIMS Class

Oestrogens, Progesterones & Related Synthetic Drugs

ATC Classification

G03CA57 - conjugated estrogens ; Belongs to the class of natural and semisynthetic estrogens used in estrogenic hormone preparations.

Regulatory Classification

POM

Presentation/Packing

Form

Premarin Tablet tab 0.625 mg

Packing/Price

1's

Premarin Tablet

estrogens

Manufacturer:

Pfizer