Pifeltro Dosage & Drug Information

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Core Prescribing Info

Contents

Doravirine

Indications/Uses

HIV-1 w/o past or present evidence of viral resistance to NNRTI in adults, in combination w/ other antiretrovirals.

Dosage/Direction for Use

1 tab once daily. Co-administration w/ rifabutin: 1 Pifeltro tab bd.

Administration

May be taken with or without food.

Contraindications

Strong CYP450 (CYP)3A enzyme inducers which include but are not limited to: anticonvulsants (eg, carbamazepine, oxcarbazepine, phenobarb, phenytoin), androgen receptor inhibitor (eg, enzalutamide), antimycobacterials (eg, rifampin, rifapentine), cytotoxic agent (eg, mitotane), St. John's wort, lumacaftor.

MIMS Class

Antivirals

ATC Classification

J05AG06 - doravirine ; Belongs to the class of non-nucleoside reverse transcriptase inhibitors. Used in the systemic treatment of viral infections.

Regulatory Classification

POM

Presentation/Packing

Form

Pifeltro FC tab 100 mg

Packing/Price

1's

Pifeltro

doravirine

Manufacturer:

MSD