Parecoxib Mylan

Short-term treatment of acute post-op pain.

IV/IM Acute pain Initially 40 mg followed by 20 mg every 6-12 hr as required. Max daily dose: 60 mg. Elderly weighing <50 kg Reduce initial dose by 50%. Max daily dose: 40 mg. Moderate hepatic impairment (Child-Pugh class B) Max daily dose: 40 mg.

Hypersensitivity. History of serious allergic drug reaction of any type especially cutaneous reaction (eg, SJS, TEN, erythema multiforme or hypersensitivity to sulphonamides). Active peptic ulceration or GI bleeding. Patients who have experienced bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria or other allergic-type reactions after taking ASA or NSAIDs including COX-2 specific inhibitors. Inflammatory bowel disease. CHF (NYHA II-IV). Post-op pain following CABG surgery. Established ischaemic heart disease, peripheral arterial disease &/or cerebrovascular disease. Severe hepatic impairment (serum albumin <25 g/L or Child-Pugh class C). Pregnancy (3rd trimester) & lactation.

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

M01AH04 - parecoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs.

POM