Paracox

Short-term treatment of acute post-op pain.

IV/IM Acute pain management 40 mg as single or initial dose followed by 20 mg every 6-12 hr as required. Max daily dose: 60 mg. Elderly weighing <50 kg Reduce initial dose by 50%. Max daily dose: 40 mg. Moderate hepatic impairment Max daily dose: 40 mg.

Hypersensitivity to parexocib or sulphonamides. History of serious allergic drug reaction of any type especially cutaneous reactions (eg, SJS, TEN, erythema multiforme). Patients who have experienced bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria or other allergic-type reactions after taking ASA or NSAIDs including other COX-2 specific inhibitors. Active peptic ulceration or GI bleeding. Inflammatory bowel disease. CHF (NYHA II-IV). Post-op pain treatment following CABG surgery. Ischemic heart disease, peripheral arterial disease &/or cerebrovascular disease. Severe hepatic impairment (serum albumin <25 g/L or Child Pugh class C). Pregnancy (3rd trimester). Lactation.

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

M01AH04 - parecoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs.

POM