OxyNorm IV Dosage & Drug Information

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Core Prescribing Info

Contents

Oxycodone HCl

Indications/Uses

Moderate to severe pain in patients w/ cancer & post-op pain. Severe pain requiring strong opioid use.

Dosage/Direction for Use

Adult >18 yr IV bolus 1-10 mg slowly over 1-2 min. Max dose interval: 4 hrly. IV infusion Starting dose: 2 mg/hr. IV PCA 0.03 mg/kg w/ a min lock-out time of 5 min. SC bolus Use as 10 mg/mL conc. Starting dose: 5 mg at 4-hr intervals. Opioid-naïve patient SC infusion Starting dose: 7.5 mg daily titrating gradually according to symptom control. Transferring patient between oral & parenteral oxycodone Dose ratio: 2 mg oral dose is equiv to 1 mg parenteral dose. Renal & hepatic impairment Reduce adult starting dose by 50% & titrate to adequate pain control according to the clinical situation. Elderly Administer the lowest dose w/ careful titration.

Contraindications

Hypersensitivity. Resp depression; head injury; paralytic ileus; acute abdomen; chronic obstructive airways disease; cor pulmonale; chronic bronchial asthma; hypercarbia; chronic constipation; concurrent administration of MAOIs or w/in 2 wk of discontinuation of their use. Moderate to severe hepatic impairment. Severe renal impairment (CrCl <10 ml/min). Pregnancy.

MIMS Class

Analgesics (Opioid)

ATC Classification

N02AA05 - oxycodone ; Belongs to the class of natural opium alkaloids. Used to relieve pain.

Regulatory Classification

POM

Presentation/Packing

Form

OxyNorm IV soln for inj 10 mg/mL

Packing/Price

1's

OxyNorm IV

oxycodone

Manufacturer:

Rafa Laboratories