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Core Prescribing Info
Contents
Sunitinib
Indications/Uses
Unresectable &/or metastatic malignant GI stromal tumor (GIST) after failure of imatinib mesylate due to resistance or intolerance. Advanced &/or metastatic renal cell carcinoma (MRCC). Unresectable or metastatic well-differentiated pancreatic neuroendocrine tumors (pNET) w/ disease progression.
Dosage/Direction for Use
GIST & MRCC 50 mg once daily for 4 consecutive wk followed by 2-wk off period (sched 4/2) to comprise a complete cycle of 6 wk. pNET 37.5 mg once daily w/o scheduled rest period.