Nexviazyme Dosage & Drug Information

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Core Prescribing Info

Contents

Avalglucosidase alfa

Indications/Uses

Long-term enzyme replacement therapy for patients w/ Pompe disease (acid α-glucosidase deficiency).

Dosage/Direction for Use

IV 20 mg/kg once every 2 wk. Infantile-onset Pompe disease patient Increase dose to 40 mg/kg every other wk in the absence of safety concerns (eg, severe hypersensitivity, anaphylactic reactions or risk of fluid overload). Decrease dose to 20 mg/kg every other wk if unable to tolerate 40 mg/kg every other wk.

Contraindications

Life-threatening hypersensitivity when re-challenge was unsuccessful.

MIMS Class

Other Agents Affecting Metabolism

ATC Classification

A16AB22 - avalglucosidase alfa ; Belongs to the class of enzymes. Used in the treatment of alimentary tract and metabolism problems.

Regulatory Classification

POM

Presentation/Packing

Form

Nexviazyme powd for soln for inj 100 mg

Packing/Price

1's

Nexviazyme

avalglucosidase alfa

Manufacturer:

Genzyme Ireland