Hypersensitivity. Severe resp depression w/ hypoxia &/or hypercapnia, severe bronchial asthma or COPD, head injury, paralytic ileus, biliary colic, acute abdomen or hepatic disease, delayed gastric emptying, cardiac arrhythmias, known morphine sensitivity. Concurrent administration of MAOIs or w/in 2 wk of discontinuation. Not recommended for pre-op use or for the 1st 24 hr post-op. Pregnancy. Childn.