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Lucentis/Lucentis PFS

Lucentis/Lucentis PFS

ranibizumab

Manufacturer:

Novartis Manufacturing NV
Information is sourced from publicly available references. The information is for educational purpose of healthcare professionals and we are not liable for any loss or damage.
Core Prescribing Info
Contents
Ranibizumab
Indications/Uses
Neovascular (wet) age-related macular degeneration (AMD); visual impairment due to diabetic macular edema (DME), macular edema secondary to retinal vein occlusion (branch or central RVO) & choroidal neovascularization (CNV); proliferative diabetic retinopathy (PDR) in adults. Retinopathy of prematurity (ROP) w/ zone 1 (stage 1+, 2+, 3 or 3+), zone 2 (stage 3+) or AP-ROP (aggressive posterior ROP) disease in preterm infants.
Dosage/Direction for Use
Adult 0.3 mg or 0.5 mg mthly as single intravitreal inj. The interval between 2 doses should not be <1 mth. Max: 0.5 mg. Only 1 eye should be injected on each occasion & post-inj monitoring is recommended. PDR 0.5 mg. Wet AMD, DME, PDR, macular edema secondary to RVO, CNV or CNV secondary to pathologic myopia (PM) Treatment should be given mthly until visual acuity is achieved &/or there no signs of disease activity. Initially ≥3 consecutive mthly inj may be needed for wet AMD, DME, PDR & RVO. May extend treatment interval by 2 wk at a time for wet AMD or by 1 mth at a time for DME. Concomitant therapy w/ laser photocoagulation in DME & branch RVO When given on the same day, administer Lucentis at least 30 min after laser photocoagulation. Preterm infant ROP 0.2 mg as single intravitreal inj. May be given bilaterally on the same day. The interval between 2 doses injected into the same eye should be at least 4 wk.
Contraindications
Hypersensitivity. Patients w/ active or suspected ocular or periocular infections; active intraocular inflammation.
MIMS Class
Other Eye Preparations
ATC Classification
S01LA04 - ranibizumab ; Belongs to the class antineovasculatisation agents. Used in the management of neovascular macular degeneration.
Presentation/Packing
Form
Lucentis PFS soln for inj 1.65 mg/0.165 mL
Packing/Price
1's
Form
Lucentis soln for inj 10 mg/mL
Packing/Price
1's
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