Linezolid Sandoz

Adults & adolescents ≥12 yr w/ infections caused by susceptible strains of gm +ve bacteria. Community-acquired pneumonia caused by penicillin-sensitive Strep pneumoniae including cases w/ concurrent bacteremia or methicillin-sensitive Staph aureus. Nosocomial pneumonia caused by Staph aureus (methicillin-sensitive & -resistant strains) or penicillin-sensitive Strep pneumoniae. Uncomplicated skin & soft tissue infections caused by methicillin-sensitive Staph aureus or Strep pyogenes. Complicated skin & soft tissue infections caused by Staph aureus (methicillin-sensitive & -resistant strains), Strep pyogenes or Strep agalactiae. Vancomycin-resistant Enterococcus faecium including cases w/ concurrent bacteremia.

Community-acquired & nosocomial pneumonia; complicated skin & soft tissue infections Adult & adolescent ≥12 yr 600 mg every 12 hr for 10-14 days. Uncomplicated skin & soft tissue infections Adult 400 mg every 12 hr for 10-14 days. Adolescent 600 mg every 12 hr for 10-14 days. Vancomycin-resistant enterococcus infections Adult & adolescent ≥12 yr 600 mg every 12 hr for 14-28 days.

May be taken with or without food: Swallow whole w/ some water.

Hypersensitivity. Concomitant use w/ MAOIs or w/in 2 wk of taking any such medicinal product. Patients w/ uncontrolled HTN, pheochromocytoma, thyrotoxicosis &/or those taking directly- & indirectly-acting sympathomimetics (eg, pseudoephedrine, phenylpropanolamine), vasopressive agents (eg, epinephrine, norepinephrine), dopaminergic agents (eg, dopamine, dobutamine). Patients w/ carcinoid syndrome &/or those taking SSRIs, TCAs, serotonin 5-HT1 receptor agonists (triptans), meperidine or buspirone.

Other Antibiotics

J01XX08 - linezolid ; Belongs to the class of other antibacterials. Used in the systemic treatment of infections.

POM