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Core Prescribing Info
Contents
Letrozole
Indications/Uses
Adjuvant treatment of postmenopausal women w/ hormone receptor +ve invasive early breast cancer. Extended adjuvant treatment of invasive early breast cancer in postmenopausal women who have received prior standard adjuvant tamoxifen therapy for 5 yr. 1st-line treatment in postmenopausal women w/ hormone-dependent advanced breast cancer. Treatment of advanced breast cancer after relapse or progression of the disease in women w/ natural or artificially induced postmenopausal endocrine state, who have been previously treated w/ anti-estrogens.
Dosage/Direction for Use
2.5 mg daily. Adjuvant & extended adjuvant setting Continue for 5 yr or until disease relapse/recurrence, whichever comes first. Advanced or metastatic breast cancer Continue until the progression of the tumor is evident.