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Indications/Uses
Monotherapy for adult patients w/ recurrent or advanced mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) endometrial cancer (EC) that has progressed on or following prior treatment w/ platinum-containing regimen. In combination w/ carboplatin & paclitaxel for adult patients w/ dMMR/MSI-H primary advanced or recurrent EC & who are candidates for systemic therapy.
Dosage/Direction for Use
IV Adult Monotherapy 500 mg infusion over 30 min every 3 wk for 4 cycles followed by 1,000 mg every 6 wk for all cycles thereafter. In combination w/ carboplatin & paclitaxel 500 mg infusion over 30 min every 3 wk for 6 cycles followed by 1,000 mg every 6 wk for all cycles thereafter.
L01FF07 - dostarlimab ; Belongs to the class of PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors. Used in the treatment of cancer.