Fludara Dosage & Drug Information

Concise Prescribing Info

Contents

Fludarabine phosphate

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Indications/Uses

B-cell chronic lymphocytic leukaemia in patients w/ sufficient bone marrow reserves. 1st-line treatment in patients w/ advanced disease, Rai stages III/IV (Binet stage C) or Rai stages I/II (Binet stage A/B) where the patient has disease-related symptoms or evidence of progressive disease.

Dosage/Direction for Use

IV Adult 25 mg/m² daily for 5 consecutive days every 28 days. Renal impairment (CrCl 30-70 mL/min) Reduce dose up to 50%.

Contraindications

Hypersensitivity. Decompensated haemolytic anaemia. Renal impairment w/ CrCl <30 mL/min. Lactation.

MIMS Class

Cytotoxic Chemotherapy

ATC Classification

L01BB05 - fludarabine ; Belongs to the class of antimetabolites, purine analogues. Used in the treatment of cancer.

Regulatory Classification

POM

Presentation/Packing

Form

Fludara powd for inj 50 mg

Packing/Price

1's

Fludara

fludarabine

Manufacturer:

Intendis