Fentanyl Martindale Pharma

Provides analgesia during short surgical procedures in low doses. Analgesic/resp depressant in patients requiring assisted ventilation in high doses. In combination w/ a neuroleptic in the technique of neuroleptanalgesia.

IM Premedicant Administer 1-2 mL 45 min before induction of anaesth. IV Adult & childn Inidividualised dosing according to age, body wt, physical status, underlying pathological condition, use of other drugs & type of surgery & anaesth. Adult Spontaneous respiration Initial: 50-200 mcg; supplemental: 50 mcg. Assisted ventilation Initial: 300-3,500 mcg; supplemental: 100-200 mcg. Unpremedicated adult 2 mL may be expected to provide sufficient analgesia for 10-20 min in surgical procedures involving low pain intensity; 10 mL as bolus given analgesia lasting about 1 hr for surgery involving moderately painful procedures; 50 mcg/kg will provide intense analgesia for some 4-6 hr for intensely stimulating surgery. Ventilated patient Loading dose: 50 mcg/mL as a fast infusion of approx 1 mcg/kg/min for the 1st 10 min followed by an infusion of approx 0.1 mcg/kg/min. Alternatively, loading dose may be given as bolus. Paed Initially 3-5 mcg/kg followed as required by 1 mcg/kg. May be increased up to a max of 15 mcg/kg, followed as required by 1-3 mcg/kg if breathing is artificially assisted.

Hypersensitivity. Resp depression, obstructive airways disease. Concurrent administration w/ MAOIs or w/in 2 wk of their discontinuation. Known intolerance to fentanyl citrate or other morphinomimetics.

Analgesics (Opioid)

N01AH01 - fentanyl ; Belongs to the class of opioid anesthetics. Used as general anesthetics.

POM