Adult Initially 50-100 mcg daily, adjusted at 3-4 wk intervals by 50 mcg until attainment of clinical & biochemical euthyroidism. Usual dose: 100-200 mcg daily.
Patient >50 yr Max initial dose: 50 mcg daily.
Cardiac disease 25 mcg daily or 50 mcg on alternate days, may be increased by 25 mcg at intervals of 4 wk.
Congenital hypothyroidism Infant Initially 25 mcg daily w/ increments of 25 mcg every 2-4 wk until optimal response is achieved.
Juvenile myxoedema Childn >1 yr Initially 2.5-5 mcg/kg daily.