Improve glycemic control as an adjunct to diet & exercise in adults w/ type 2 DM as monotherapy or in combination w/ other medicinal products. Reduce risk of CV death & hospitalization for heart failure in adults w/ heart failure (NYHA class II-IV). Adjunct to standard therapy to reduce the risk of sustained eGFR decline, ESRD & CV death in adults w/ CKD at risk of progression.