Cozaar/Cozaar XQ Dosage & Drug Information

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Core Prescribing Info

Contents

Cozaar tab: Losartan K. Cozaar XQ FC tab 5/50 mg: Amlodipine camsylate 7.84 mg (equiv to amlodipine 5 mg), losartan K 50 mg. Cozaar XQ FC tab 5/100 mg: Amlodipine camsylate 7.84 mg (equiv to amlodipine 5 mg), losartan K 100 mg

Indications/Uses

Cozaar HTN. Reduction in the risk of stroke in hypertensive patients w/ left ventricular hypertrophy. Delay of renal disease progression & reduction of proteinuria. Cozaar XQ Essential hypertensive patients not adequately controlled w/ amlodipine or losartan monotherapy.

Dosage/Direction for Use

Cozaar HTN Initial & maintenance dose: 50 mg once daily, may be increased to 100 mg once daily. Patient w/ intravascular vol-depletion; moderate to severe renal impairment; on dialysis; elderly >75 yr Initially 25 mg once daily. Reduction in the risk of stroke in hypertensive patient w/ left ventricular hypertrophy Initially 50 mg once daily. A low dose of hydrochlorothiazide should be added &/or the dose of Cozaar should be increased to 100 mg once daily based on BP response. Renal protection in type 2 diabetic patient w/ proteinuria Initially 50 mg once daily, may be increased to 100 mg once daily based on BP response. May be administered w/ other antihypertensives, insulin & other commonly used hypoglycemic agents. Cozaar XQ 1 tab once daily. Recommended to be taken on a regular schedule (ie, every morning).

Administration

May be taken with or without food.

Contraindications

Hypersensitivity. Concomitant use w/ aliskiren-containing products in patients w/ DM or renal impairment (GFR <60 mL/min/1.73 m²). Cozaar XQ Hypersensitivity to losartan or dihydropyridines. Severe aortic valvular stenosis. Patient in shock. Severe hepatic impairment. Pregnancy (or those possible to be pregnant) & lactation.

MIMS Class

Angiotensin II Antagonists / Calcium Antagonists

ATC Classification

C09CA01 - losartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
C09DB06 - losartan and amlodipine ; Belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers. Used in the treatment of cardiovascular disease.

Regulatory Classification

POM

Presentation/Packing

Form

Cozaar XQ FC tab 5 mg/100 mg

Packing/Price

1's

Form

Cozaar XQ FC tab 5 mg/50 mg

Packing/Price

1's

Form

Cozaar tab 100 mg

Packing/Price

1's

Form

Cozaar tab 50 mg

Packing/Price

1's

Cozaar/Cozaar XQ

amlodipine + losartan

losartan

Manufacturer:

Organon