Clopidogrel Sandoz

Secondary prevention of atherothrombotic events in adult patients suffering from MI (from a few days until <35 days), ischaemic stroke (from 7 days until <6 mth) or established peripheral arterial disease; acute coronary syndrome [non-ST segment elevation acute coronary syndrome (unstable angina or non-Q-wave MI) including patients undergoing stent placement following percutaneous coronary intervention (PCI) in combination w/ ASA; ST segment elevation acute MI in combination w/ ASA in medically treated patients eligible for thrombolytic therapy]. In combination w/ ASA in adult patients w/ moderate to high-risk transient ischemic attack (TIA) (ABCD2 score ≥4) or minor ischemic stroke (IS) (NIHSS ≤3) within 24 hr of either the TIA or IS event; for the prevention of atherothrombotic & thromboembolic events in atrial fibrillation in adult patients who have at least 1 risk factor for vascular events, are not suitable for treatment w/ vit K antagonists (VKA) & who have a low bleeding risk.

Adult & elderly 75 mg as single daily dose. Non-ST segment elevation acute coronary syndrome (unstable angina or non-Q-wave MI) Initially 300 or 600 mg as single loading dose, followed by 75 mg once daily (w/ ASA 75-325 mg daily). Elderly <75 yr Consider a 600 mg loading dose when PCI is intended. ST segment elevation acute MI 75 mg as single daily dose, initiated w/ 300 mg loading dose in combination w/ ASA & w/ or w/o thrombolytics. Elderly >75 yr Initiate therapy w/o loading dose. Adult Moderate to high-risk TIA or minor IS 300 mg as loading dose followed by 75 mg once daily (w/ ASA 75-100 mg once daily). Start w/in 24 hr of the event & continued for 21 days followed by single antiplatelet therapy. Patient w/ atrial fibrillation 75 mg as single daily dose (w/ ASA 75-100 mg daily).

May be taken with or without food.

Hypersensitivity. Active pathological bleeding (eg, peptic ulcer or intracranial haemorrhage). Severe hepatic impairment.

Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics)

B01AC04 - clopidogrel ; Belongs to the class of platelet aggregation inhibitors excluding heparin. Used in the treatment of thrombosis.

POM