Major depressive episodes, generalised anxiety disorder & obsessive-compulsive disorder 10 mg once daily. May be increased to a max of 20 mg daily.
Panic disorder w/ or w/o agoraphobia Initially 5 mg for the 1st wk before increasing to 10 mg daily. May be further increased up to a max of 20 mg daily.
Elderly >65 yr Initially ½ the usual recommended dose & consider lower max dose.
Reduced hepatic function; poor CYP2C19 metaboliser Initially 5 mg daily for the 1st 2 wk. May be increased to 10 mg daily.