Celebrex Dosage & Drug Information

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Core Prescribing Info

Contents

Celecoxib

Indications/Uses

Symptomatic treatment of OA & RA. Management of acute pain in adults & chronic low back pain. Primary dysmenorrhea. Relief of signs & symptoms of ankylosing spondylitis (AS).

Dosage/Direction for Use

Adult OA & AS 200 mg as single dose or 100 mg bd. Max daily dose: 400 mg. RA 100 or 200 mg bd. Max daily dose: 400 mg. Acute pain & primary dysmenorrhea Initially 400 mg followed by 200 mg if needed on the 1st day. Subsequently, 200 mg bd as needed. Chronic low back pain 200 or 400 mg daily, administered as 200 mg single dose or 100-200 mg bd. Total daily dose: 400 mg. Moderate hepatic impairment (serum albumin 25-35 g/L or Child-Pugh Class B), patient co-administered w/ fluconazole & CYP2C9 poor metabolizers Initiate treatment at ½ the recommended dose.

Administration

May be taken with or without food: Doses up to 200 mg bd can be taken w/ or w/o food. For patients w/ difficulty swallowing, the entire contents of the cap can be carefully emptied onto a level tsp of cool/room temp applesauce, rice gruel, yogurt or mashed banana & should be ingested immediately w/ water.

Contraindications

Hypersensitivity to celecoxib or sulfonamides. Patients who have experienced asthma, urticaria or allergic-type reactions after taking ASA or other NSAIDs including other COX-2 specific inhibitors. Patients w/ active peptic ulceration or GI bleeding. Peri-op pain treatment in CABG surgery. CHF (NYHA II-IV). Established ischemic heart disease, peripheral arterial disease &/or cerebrovascular disease.

MIMS Class

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

ATC Classification

M01AH01 - celecoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs.

Regulatory Classification

POM

Presentation/Packing

Form

Celebrex cap 100 mg

Packing/Price

1's

Form

Celebrex cap 200 mg

Packing/Price

1's

Form

Celebrex cap 400 mg

Packing/Price

1's

Celebrex

celecoxib

Manufacturer:

Viatris Ltd